The Substance (2024), directed by Coralie Fargeat (Revenge), is a provocative body horror film that delves into themes of aging, beauty standards, and the societal pressures faced by women, particularly in the entertainment industry. Starring Demi Moore and Margaret Qualley, the film has garnered significant attention for its bold storytelling and visceral imagery.

The narrative centers on Elisabeth Sparkle (Demi Moore), a former Hollywood starlet who, after being dismissed from her aerobics TV show due to ageism, turns to an illicit substance promising rejuvenation. This mysterious liquid creates a younger, idealized version of herself named Sue (Margaret Qualley). However, the transformation comes with a caveat: Elisabeth and Sue must alternate control of the body every seven days. As Sue becomes increasingly dominant, Elisabeth’s grasp on her identity and reality begins to unravel, leading to a grotesque and tragic climax .

Fargeat’s direction is both audacious and meticulous, employing practical effects, including extensive prosthetics and over 21,000 liters of fake blood, to create a visceral experience . The film’s aesthetic draws inspiration from filmmakers like David Cronenberg and Darren Aronofsky, blending grotesque body horror with satirical elements to critique societal beauty standards.

Premiering at the 77th Cannes Film Festival, The Substance won Best Screenplay and later secured the Academy Award for Best Makeup and Hairstyling. With a box office gross between $77–82 million against an $18 million budget, it stands as Mubi’s highest-grossing film to date .